August 14, 2019

Yuichi Iwaki
Chief Executive Officer
MediciNova, Inc.
4275 Executive Square, Suite 300
La Jolla, CA 92037

       Re: MediciNova, Inc.
           Registration Statement on Form S-3
           Filed August 9, 2019
           File No. 333-233201

Dear Dr. Iwaki:

       This is to advise you that we have not reviewed and will not review your

        Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

       Please contact Donald Field at 202-551-3680 with any questions.


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