Accounts Payable Current Accounts payable Accrued Expenses [Line Items] Accrued Expenses [Line Items] Accrued Expenses [Line Items] Accrued Expenses [Table] Accrued Expenses [Table] Accrued Expenses [Table] Accrued Liabilities Current Accrued expenses Accrued expenses Accrued Professional Fees Current Professional services fees Accrued Research and Development Expense, Current Accrued Research And Development Expense Current Research and development costs Accumulated Other Comprehensive Income Loss Net Of Tax Accumulated other comprehensive loss Additional Paid In Capital Additional paid-in capital Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Amendment Flag Amendment Flag Amortization of premium or discount on investment securities, accretion of convertible notes to fair market value and amortization of debt discount and issuance costs. Amortization Of Premium Discount On Investment Securities Convertible Notes And Debt Discount And Issuance Costs Amortization of premium/discount on investment securities, convertible debt, debt discount and issuance costs Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Total Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] Aspire Capital Fund Llc [Member] Aspire Capital Fund Llc [Member] Aspire Capital Fund Llc Assets Total assets Assets [Abstract] Assets Assets Current Total current assets Assets Current [Abstract] Current assets: At Market Sales Agreement [Member] At Market Sales Agreement [Member] At Market Sales Agreement Award Type [Axis] Award Type [Axis] Basis Of Accounting Policy Policy [Text Block] Basis of Presentation Cash And Cash Equivalents At Carrying Value Cash and cash equivalents, end of period Cash and cash equivalents, beginning of period Cash and cash equivalents Cash And Cash Equivalents Fair Value Disclosure Cash equivalents Cash And Cash Equivalents Period Increase Decrease Net increase/ (decrease) in cash and cash equivalents Cash F D I C Insured Amount Cash insured amount Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Supplemental disclosure of investing and financing activities: Class Of Stock [Domain] Class of Stock [Domain] Class Of Warrant Or Right Exercise Price Of Warrants Or Rights Common share exercise price Class of Warrant or Right, Expiration Period Class Of Warrant Or Right Expiration Period Warrant, expiration period Class of Warrant or Right, Fair Value Class Of Warrant Or Right Fair Value Warrant, fair value Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Warrant issued to purchase Common shares Class Of Warrant Or Rights Exercisable Period From Date Of Issuance Class Of Warrant Or Rights Exercisable Period From Date Of Issuance Warrant, exercisable period Closing Price Of Common Stock Closing Price Of Common Stock Stock purchase agreement, closing price of common stock per share that results in not effect any sales Commitments And Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Commitments And Contingencies Disclosure [Text Block] Commitments and Contingencies Common Stock Maximum Sale Amount Under Purchase Agreement Common Stock Maximum Sale Amount Under Purchase Agreement Stock Purchase Agreement, maximum amount of sale Common Stock [Member] Common Stock Common Stock Par Or Stated Value Per Share Common stock, par value Common Stock Shares Authorized Common stock, shares authorized Common Stock Shares Issued Common stock, shares issued Common Stock Shares Outstanding Common stock, shares outstanding Common Stock Shares Subscriptions Stock purchase agreement, aggregate amount of common stock agreed to be purchased Common Stock Value Common stock, $0.001 par value; 100,000,000 shares authorized at June 30, 2013 and December 31, 2012; 22,148,493 and 17,407,311 shares issued at June 30, 2013 and December 31, 2012, respectively, and 22,148,493 and 17,403,125 shares outstanding at June 30, 2013 and December 31, 2012, respectively Comprehensive Income Net Of Tax Comprehensive loss Concentration Risk Credit Risk Concentrations and Credit Risk Consists of each firm commitment underwritten public offering unit. Consists Of Each Firm Commitment Underwritten Public Offering Unit Consists of each firm commitment underwritten public offering unit Consolidation Policy [Text Block] Principles of Consolidation Conversion Of Stock Amount Converted 1 Conversion of convertible preferred stock into common stock upon initial public offering Convertible Preferred Stock [Member] Convertible preferred stock, as converted Convertible Preferred Stock Shares Issued Upon Conversion Series B Preferred Stock, Shares Issued upon Conversion Convertible Preferred Stock Terms Of Conversion Series B Preferred stock conversion term Cost Of Revenue Cost of revenues Current Fiscal Year End Date Current Fiscal Year End Date The deemed dividend on the Series C Preferred Stock is the aggregate difference between the estimated fair value of the underlying common stock and the Series C Preferred Stock conversion price per share. The deemed dividend increased the net loss applicable to common shareholders in the calculation of basic and diluted net loss per common share. Deemed Dividend Resulting From Convertible Preferred Stock Deemed dividend resulting from beneficial conversion feature on Series C redeemable convertible preferred stock Deferred Revenue Deferred revenue related to research and development services Deferred Revenue Current Current deferred revenue Deferred Revenue Noncurrent Long-term deferred revenue Deferred Revenue Period Increase Decrease Amortization of Kissei upfront payment Deferred Tax Liabilities Noncurrent Deferred tax liability Depreciation Depletion And Amortization Depreciation and amortization Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Stock-Based Compensation Document Document and Entity Information [Abstract] Document Document And Entity Information [Abstract] Document Documentand Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Information [Line Items] Document Information [Line Items] Document Period End Date Document Period End Date Document Type Document Type Earnings Per Share [Abstract] Earnings Per Share [Abstract] Earnings Per Share Basic And Diluted Basic and diluted net loss per common share Earnings Per Share [Text Block] Net Loss Per Share Employee Related Liabilities Current Accrued compensation and related expenses Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Unamortized compensation cost Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition 1 Unamortized compensation cost, vesting period Employee Stock [Member] ESPP Employee Stock Option [Member] Stock Options Employee Stock Purchase Plan Share Purchase Offering Period Employee Stock Purchase Plan Share Purchase Offering Period Employee stock purchase plan offering period Entities [Table] Entities [Table] Entity Central Index Key Entity Central Index Key Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Entity [Domain] Entity [Domain] Entity Filer Category Entity Filer Category Entity Registrant Name Entity Registrant Name Equity [Abstract] Equity [Abstract] Equity Component [Domain] Equity Component [Domain] Equity Distribution Agreement [Member] Equity Distribution Agreement [Member] Equity Distribution Agreement Equity Issuance Per Share Amount Shares purchase & equity issuance, per share amount Equity Method Investment Ownership Percentage Investment in China joint venture, percentage Percentage of outstanding voting stock Equity Method Investments And Joint Ventures [Abstract] Equity Method Investments and Joint Ventures [Abstract] Equity Method Investments Disclosure [Text Block] Joint Venture Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Table [Text Block] Fair Value Measurements on Recurring Basis Fair Value By Fair Value Hierarchy Level [Axis] Fair Value, Hierarchy [Axis] Fair Value By Measurement Frequency [Axis] Measurement Frequency [Axis] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value Inputs Level 1 [Member] Fair Value Measurements Using Level 1 Fair Value Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Fair Value Measurement Inputs Disclosure [Text Block] Fair Value Measurements Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value Measurements Recurring [Member] Fair Value, Measurements, Recurring Gain Loss On Disposition Of Assets (Gain)/loss on disposal of assets General And Administrative Expense General and administrative Goodwill Goodwill Impairment charge or (gain), net on trading investment securities and ARS put based on fair market value as determined on a Level 3 basis pursuant to a discounted cash flow model. Impairment Charge Gain Net On Investment Securities And Ars Put Impairment charge, net on investment securities and ARS Put Impairment (write-down) of tenant improvements of sublet office space due to non-utility. Impairment Of Sublease Impairment of sublease Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments Loss before income taxes Income Statement [Abstract] Income Statement [Abstract] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Income Taxes Paid Income taxes paid Income Tax Expense Benefit Income taxes The net change during the reporting period in the aggregate amount of accounts payable, accrued expenses, income taxes payable , deferred rent, and other similar obligations and liabilities. Increase Decrease In Accounts Payable Accrued Expenses Income Taxes Payable And Deferred Rent Accounts payable, income tax payable, accrued expenses and deferred rent Increase Decrease In Deferred Revenue Deferred Revenue Increase Decrease In Employee Related Liabilities Accrued compensation and related expenses Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase Decrease In Prepaid Deferred Expense And Other Assets Prepaid expenses and other assets Increase Decrease Of Restricted Investments Restricted assets Carrying amount as of the balance sheet date, which is the fair value of the acquired in-process technology, adjusted for any amortization recognized after market feasibility has been achieved and for any impairment charges. In Process Research And Development In-process research and development Interest Expense Interest expense Interest Paid Interest paid Investments In Affiliates Subsidiaries Associates And Joint Ventures Investment in joint venture Investor One [Member] Investor One [Member] Investor One Investors Name [Axis] Investors Name [Axis] Investors Name [Axis] Investors Name [Domain] Investors Name [Domain] Investors Name [Domain] Legal Entity [Axis] Legal Entity [Axis] Liabilities Total liabilities Liabilities And Stockholders Equity Total liabilities and stockholders' equity Liabilities And Stockholders Equity [Abstract] Liabilities and Stockholders' Equity Liabilities Current Total current liabilities Liabilities Current [Abstract] Current liabilities: Loss Contingencies [Line Items] Loss Contingencies [Line Items] Loss Contingencies [Table] Loss Contingencies [Table] Loss Contingency Damages Sought Value Awarded monetary sanction amount Macquarie Capital Incorporated [Member] Macquarie Capital Incorporated [Member] Macquarie Capital Incorporated Maturity period of investment in cash equivalents securities. Maturity Period Of Investment In Cash Equivalents Securities Instruments maturities Maximum [Member] Maximum Minimum [Member] Minimum Net Cash Provided By Used In Financing Activities Net cash provided by financing activities Net Cash Provided By Used In Financing Activities [Abstract] Financing activities: Net Cash Provided By Used In Investing Activities Net cash used in investing activities Net Cash Provided By Used In Investing Activities [Abstract] Investing activities: Net Cash Provided By Used In Operating Activities Net cash used in operating activities Net Cash Provided By Used In Operating Activities [Abstract] Operating activities: Net Income Loss Net loss Net loss Net Income Loss Available To Common Stockholders Basic Net loss applicable to common stockholders Net loss applicable to common stockholders Noncash Or Part Noncash Acquisition Noncash Financial Or Equity Instrument Consideration Warrants Issued 1 Proceeds from issuance of warrants Number Of Consecutive Business Day Number Of Consecutive Business Day Stock purchase agreement, number of consecutive business days required to determine purchase price Number of Lowest Closing Stock Prices Number Of Lowest Closing Stock Prices Stock purchase agreement, number of lowest closing stock prices to determine purchase price Number of units in firm commitment underwritten public offering. Number Of Units In Firm Commitment Underwritten Public Offering Number of units in firm-commitment underwritten public offering Operating Expenses Total operating expenses Operating Expenses [Abstract] Operating expenses: Operating Income Loss Operating loss Option Indexed To Issuers Equity Type [Axis] Option Indexed to Issuer's Equity, Type [Axis] Option Indexed To Issuers Equity Type [Domain] Option Indexed to Issuer's Equity, Type [Domain] Organization Consolidation And Presentation Of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Other Accrued Liabilities Current Other Other Asset Amortization Period Other Asset Amortization Period Warrant, amortization period Other Comprehensive Income Loss Foreign Currency Transaction And Translation Adjustment Net Of Tax Foreign currency translation adjustments Other Comprehensive Income Loss Net Of Tax Period Increase Decrease [Abstract] Other comprehensive loss, net of tax: Other Nonoperating Expense Other expense Other Nonoperating Income Other income Payables And Accruals [Abstract] Payables and Accruals [Abstract] Payments Of Stock Issuance Costs Cost related to private placement Payments To Acquire Businesses Net Of Cash Acquired Cash paid for acquired business, net of acquired cash Payments To Acquire Interest In Joint Venture Investment in China joint venture Investment in joint venture Payments To Acquire Investments Purchases of investment securities Payments To Acquire Property Plant And Equipment Acquisition of property and equipment Preferred Stock Accretion Of Redemption Discount Accretion to redemption value of redeemable convertible preferred stock Preferred Stock Par Or Stated Value Per Share Preferred stock, par value Series B Convertible Preferred Stock par value Preferred Stock Shares Authorized Preferred stock, shares authorized Preferred Stock Shares Issued Preferred stock, shares issued Preferred Stock Shares Outstanding Preferred stock, shares outstanding Preferred Stock Value Preferred stock, $0.01 par value; 3,000,000 shares authorized at June 30, 2013 and December 31, 2012; 220,000 shares issued and outstanding at June 30, 2013 and December 31, 2012 Prepaid Expense And Other Assets Current Prepaid expenses and other current assets Private Placement [Member] Private Placement Proceeds from the conversion of convertible notes into common stock. Proceeds From Conversion Of Convertible Notes Proceeds from conversion of convertible notes Proceeds From Issuance Of Common Stock Stock purchase agreement, proceeds Common Stock purchase agreement, proceeds from sale Proceeds from issuance of common stock and units, net of issuance costs Proceeds From Issuance Of Common Stock Gross Proceeds From Issuance Of Common Stock Gross Common Stock purchase agreement, gross proceeds from sale Proceeds From Issuance Of Debt Net proceeds from debt Proceeds From Issuance Of Preferred Stock And Preference Stock Proceeds from issuance of convertible preferred stock, net of issuance costs Proceeds From Issuance Of Private Placement Aggregate purchase price for shares and warrants under private placements Proceeds from Issuance of Private Placement Net Proceeds From Issuance Of Private Placement Net Net Proceeds form issuance of shares and warrants in private placement Proceeds From Other Debt Proceeds from ARS loan Proceeds From Sale And Maturity Of Marketable Securities Maturities or sales of investment securities Proceeds From Sale Of Property Plant And Equipment Proceeds from sales of property and equipment Proceeds From Stock Options Exercised Proceed from stock options exercised Proceeds From Warrant Exercises Proceeds from exercise of warrants Proceeds Or Payments For Issuance Or Repurchase Of Common Stock Net Proceeds Or Payments For Issuance Or Repurchase Of Common Stock Net Purchase of treasury stock, net of employee stock purchases Property Plant And Equipment Net Property and equipment, net Quarterly Financial Information Disclosure [Abstract] Quarterly Financial Information Disclosure [Abstract] Quarterly Financial Information [Line Items] Quarterly Financial Information [Line Items] Quarterly Financial Information [Line Items] Quarterly Financial Information [Table] Quarterly Financial Information [Table] Quarterly Financial Information [Table] Quarterly Financial Information [Text Block] Interim Financial Information