06061 - Disclosure - Net Loss Per Share (Details Textual) link:presentationLink link:calculationLink link:definitionLink 0506 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 0603 - Disclosure - Joint Venture (Details) link:presentationLink link:calculationLink link:definitionLink 0203 - Disclosure - Joint Venture link:presentationLink link:calculationLink link:definitionLink 06091 - Disclosure - Stock-Based Compensation (Details Textual) link:presentationLink link:calculationLink link:definitionLink 0610 - Disclosure - Income Taxes (Details Textual) link:presentationLink link:calculationLink link:definitionLink 0601 - Disclosure - Interim Financial Information (Details) link:presentationLink link:calculationLink link:definitionLink 06121 - Disclosure - Stockholders' Equity (Details Textual) link:presentationLink link:calculationLink link:definitionLink 0612 - Disclosure - Stockholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 0609 - Disclosure - Stock-Based Compensation (Details) link:presentationLink link:calculationLink link:definitionLink 0608 - Disclosure - Balance Sheet Detail (Details) link:presentationLink link:calculationLink link:definitionLink 0607 - Disclosure - Accumulated Other Comprehensive Loss (Details) link:presentationLink link:calculationLink link:definitionLink 0606 - Disclosure - Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 0605 - Disclosure - Long-term Debt (Details) link:presentationLink link:calculationLink link:definitionLink 0604 - Disclosure - Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 0602 - Disclosure - Avigen Transaction (Details) link:presentationLink link:calculationLink link:definitionLink 0512 - Disclosure - Stockholders' Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 0509 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 0508 - Disclosure - Balance Sheet Details (Tables) link:presentationLink link:calculationLink link:definitionLink 0507 - Disclosure - Accumulated Other Comprehensive Loss (Tables) link:presentationLink link:calculationLink link:definitionLink 0504 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 0401 - Disclosure - Interim Financial Information (Policies) link:presentationLink link:calculationLink link:definitionLink 0212 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 0211 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 0210 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 0209 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 0208 - Disclosure - Balance Sheet Details link:presentationLink link:calculationLink link:definitionLink 0207 - Disclosure - Accumulated Other Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 0206 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 0205 - Disclosure - Long-term Debt link:presentationLink link:calculationLink link:definitionLink 0204 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 0202 - Disclosure - Avigen Transaction link:presentationLink link:calculationLink link:definitionLink 0201 - Disclosure - Interim Financial Information link:presentationLink link:calculationLink link:definitionLink 0130 - Statement - Consolidated Statements of Cash Flows (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0120 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0111 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 0110 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 00 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink